Whether you're envisioning a signature business, an inspired live-work space, or a long-term investment in downtown Guelph, 143 Norfolk St. is ready for its next chapter. With D2 (Specialized Downtown) zoning, this distinctive building is well suited for a wide range of residential, commercial, or mixed-use possibilities. Spanning ~4,049 sq. ft., the handsomely finished interior includes a spacious kitchen, 10 offices, 4 bathrooms, a third-floor attic, and additional storage space in the lower level, providing room to adapt as your needs evolve. Alternatively, imagine a sophisticated residence on the upper levels complemented by boutique retail, professional offices, wellness services, or a creative studio space below. Throughout the property, beautifully preserved architectural details celebrate its historic roots. From soaring ceilings and rich woodwork to elegant pocket doors, oversized baseboards, a graceful sweeping staircase, a striking stained glass keyhole window, and an enchanting turret, every space tells a story of craftsmanship and character. Outside, a secluded courtyard enclosed by wrought iron fencing creates a peaceful outdoor setting that is both charming and unexpectedly private. Adding to its appeal is a detached 610 sq. ft. coach house with electrical already in place. Whether used as a private office, workshop, studio, or explored as a potential accessory apartment, it offers valuable flexibility that's increasingly difficult to find in the downtown core. Just minutes from the new Guelph Central Library and the Baker District redevelopment, you will be surrounded by the energy, walkability, and convenience that make downtown Guelph one of the city's most sought-after destinations. Rarely does a property combine this level of history, flexibility, and location.